Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
$89$8.90/mg
28-amino-acid thymic peptide — T-cell and immune signalling research
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Thymosin Alpha 1 · 10mg
Frequently bought together
Researchers usually add these to complete the protocol.
BAC Water · 3ml
Essential · Extras
GHK-CU · 50mg
Recovery
Melanotan 2 · 10mg
Tanning
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Vantage Analytical
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Purity ≥98%
Know your compound
Thymosin Alpha-1 (Tα1) is a 28-amino-acid peptide originally isolated from thymic tissue, now produced as a synthetic sequence for research use. It is catalogued under the pharmaceutical designation Zadaxin and is registered as an approved therapeutic in over 30 countries, providing an unusually large base of clinical trial data for a research peptide.
Over 70 clinical trials have examined its effects on T-cell maturation, dendritic cell activation, and viral response markers — a breadth of clinical investigation that is rare among peptide research tools. Preclinical and clinical work has also documented effects on tumour-associated macrophage polarisation, extending its relevance beyond infectious disease models into immuno-oncology research.
For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
Published research on the reference compound class. Provided for scientific context only — not a claim about the product supplied.
Across hepatitis B, hepatitis C, HIV, and sepsis, over 70 clinical trials have examined Thymosin Alpha 1's immune effects — a depth of investigation that is rare for any research peptide.
Indicative distribution of >70 trials across documented indications. World Journal of Virology, 2020.
In a murine tumour model, Thymosin Alpha 1 reversed the immunosuppressive M2 phenotype of tumour-associated macrophages toward a pro-inflammatory M1 state during efferocytosis — a directional shift that may matter for immuno-oncology research.
Directional representation only — no precise counts reported in abstract. Murine efferocytosis assay, Cancer Research 2022.
Across multiple in vitro assays and human clinical samples, Thymosin Alpha 1 promoted T-cell maturation and dendritic cell activation; the magnitude of response varied with the subject's baseline immune status.
Thymic origin
Isolated from thymic tissue; T-cell maturation effects identified
In vitro evidence
TCR signalling & dendritic cell activation documented in cell assays
Clinical samples
Human immunomodulation confirmed; response varies with immune baseline
Ongoing review
Vitamins & Hormones 2016 comprehensive literature synthesis
Evidence trajectory across model systems. No precise quantitative endpoint available; directional summary only.
Mechanism
Tα1 is studied through three distinct biological routes: modulation of T-cell receptor signalling, regulation of innate immune cell polarisation, and activation of pattern-recognition receptor pathways.
Tα1 is investigated for its capacity to promote T-cell maturation and enhance T-cell receptor-mediated signalling, particularly in contexts where thymic output or T-cell responsiveness is reduced.
Preclinical studies indicate that Tα1 can reverse M2-type (anti-inflammatory, tumour-permissive) macrophage polarisation toward an M1-type profile, a mechanism under investigation in immuno-oncology models.
Research suggests Tα1 engages Toll-like receptor pathways on dendritic cells, promoting innate immune activation and downstream interferon signalling in response to pathogen-associated stimuli.
For research use only. Mechanisms described reflect published preclinical and clinical literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
Best sellers
FAQ
Common questions about Thymosin Alpha 1
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.
