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Independently verifiedCertified

GHK-CU · 100mg

Purity (HPLC)≥98%

LabVantage Analytical

Tested28 Jun 2026

Batch —·

Heavy metalsEndotoxinsMicrobialSolvents

View full COA

In stock

GHK-CU

Name: GHK-CU
Brand: AXOS
Availability: InStock

$59$0.59/mg

Copper-binding tripeptide — gene expression and tissue repair research

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Independently verifiedCertified

GHK-CU · 100mg

Purity (HPLC)≥98%

LabVantage Analytical

Tested28 Jun 2026

Batch —·

Heavy metalsEndotoxinsMicrobialSolvents

View full COA

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity
Raw chromatogram + mass confirmation attached
Signed off by the lab's Principal Chemist
Permanent archive — searchable by lot ID

View all lab reports

Reference reportView All Live Reports

Vantage Analytical

Independent analytical lab

Certificate of Analysis

RESULT · PASS

ProductGHK-CU · 100mg

Lot / batch—

Reported28 Jun 2026

MethodHPLC-UV + LC-MS

AppearanceWhite lyophilized powder

ClientSolace Peptides

Analytical results

Identity (LC-MS)1419.5 DaPASS

Purity (HPLC-UV)≥98%PASS

Net content10.2 mgPASS

Endotoxin (LAL)< 0.05 EU/mgPASS

Heavy metals (ICP-MS)< 10 ppmPASS

Residual solventsBelow LOQPASS

HPLC Chromatogram

Purity ≥98%

Chemist verifiedDr. E. Hartley

Know your compound

What is GHK-CU?

GHK-Cu (glycyl-l-histidyl-l-lysine copper(II)) is a naturally occurring tripeptide–copper complex isolated from human plasma, with molecular formula C14H23CuN6O4 and MW 340.84 Da (free peptide). It is investigated as a modulator of gene transcription, extracellular matrix remodeling, and oxidative stress pathways in preclinical models.

A landmark gene-expression analysis found GHK-Cu modulated 4,192 human genes, with collagen biosynthesis and antioxidant response pathways among those significantly upregulated — a breadth of transcriptional influence that has made it a priority target in aging biology and wound-repair research. Secondary areas of investigation include pulmonary fibrosis, sarcopenia, and angiogenesis, each addressed in peer-reviewed animal or in vitro models.

Modulated 4,192 human genes toward younger expression patterns in transcriptomic analysis (Pickart & Margolina, 2018)
Attenuated bleomycin-induced pulmonary fibrosis in murine models via anti-oxidative and anti-inflammatory pathways
Accelerated scald-wound closure in mice by promoting cell proliferation and angiogenesis (Wang et al., 2017)

Lot-specific COAEvery lot ships with an HPLC Certificate of Analysis and mass-spectrometry identity confirmation.

Institutional fulfilmentShipped to verified institutional addresses with full analytical documentation.

Lot-specific COA: Every lot ships with an HPLC Certificate of Analysis and mass-spectrometry identity confirmation.
Institutional fulfilment: Shipped to verified institutional addresses with full analytical documentation.

For research use only — not for human or veterinary use.

The research

What the research actually found

The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.

Published research on the reference compound class. Provided for scientific context only — not a claim about the product supplied.

Gene activityPreclinical

4,192

A bioinformatic analysis of human gene-expression databases found GHK-Cu associated with altered expression of 4,192 human genes — spanning collagen biosynthesis, antioxidant response, and tissue-repair pathways — suggesting an unusually broad transcriptional footprint for a single peptide.

in silico · human gene databases

International Journal of Molecular Sciences, 2018 · Pickart & Margolina

GHK-Cu modulated genes4,192 genesUnaffected genes~15,800 genes

Proportion of the ~20,000 protein-coding human genes with expression altered in the GHK-Cu transcriptomic analysis (bioinformatic model; not a clinical finding).

Lung fibrosisPreclinical

In a bleomycin-induced pulmonary fibrosis mouse model, GHK-Cu-treated animals showed reduced lung collagen deposition and lower oxidative stress and inflammatory markers compared with vehicle controls, suggesting anti-fibrotic activity via antioxidant and anti-inflammatory pathways.

vs. vehicle control · bleomycin mouse model

Vehicle controlhigher fibrosis score

GHK-Cu treatedreduced fibrosis score

Directional comparison — bleomycin-injured mouse lung; exact % reduction not reported in abstract. Bar heights reflect relative directionality only, not precise magnitudes.

Life Sciences, 2020 · Ma et al.

Wound healingPreclinical

In a murine scald-wound model, animals treated with GHK-Cu liposomes showed faster macroscopic wound closure and greater vascular density on histology compared with vehicle liposome and untreated controls, pointing to accelerated repair via cell proliferation and angiogenesis.

vs. vehicle liposome & untreated · mouse scald model

Untreated controlslower closure

Vehicle liposomemarginal improvement

GHK-Cu liposomefastest closure

Directional comparison — murine scald-wound model; quantitative closure % not reported in abstract. Bar heights reflect relative directionality only.

Wound Repair and Regeneration, 2017 · Wang et al.

Gene modulationtranscriptional reprogramming

ECM remodelingMMP / TIMP axis

Redox regulationantioxidant pathway

Mechanism

How GHK-CU works

GHK-Cu is studied to act through three distinct molecular routes: transcriptional reprogramming, extracellular matrix remodeling, and redox regulation.

Gene modulationtranscriptional reprogramming

GHK-Cu is studied to interact with DNA-binding regulatory elements, shifting gene expression profiles across pathways involved in collagen biosynthesis, growth factor signaling, and cellular senescence in transcriptomic analyses.

ECM remodelingMMP / TIMP axis

Preclinical models indicate GHK-Cu influences matrix metalloproteinase and tissue inhibitor of metalloproteinase balance, promoting extracellular matrix turnover and collagen deposition relevant to wound-repair research.

Redox regulationantioxidant pathway

In murine fibrosis and muscle-dysfunction models, GHK-Cu has been associated with suppression of reactive oxygen species and downstream inflammatory mediators, implicating copper-chelation chemistry in its antioxidant activity.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

The process

How every batch is verified

01
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
02
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
03
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
04
COA published
The certificate is posted to the open library, by lot, before the vial ships.

Verified researchers

Reviewed by people who test it themselves

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FAQ

Frequently asked

Common questions about GHK-CU

The COA guarantee

≥98% pure — or your money back.

Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.

Order with cover

Third-party tested

An independent, accredited lab — no commercial interest in the result.

A COA on every lot

A lot-specific certificate ships with each vial, archived by batch.

Test it yourself → refund

Re-test any batch at any lab. A mismatch is a full refund.

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity

Raw chromatogram + mass confirmation attached

Signed off by the lab's Principal Chemist

Permanent archive — searchable by lot ID

View all lab reports

What is GHK-CU?

Modulated 4,192 human genes toward younger expression patterns in transcriptomic analysis (Pickart & Margolina, 2018)

Attenuated bleomycin-induced pulmonary fibrosis in murine models via anti-oxidative and anti-inflammatory pathways

Accelerated scald-wound closure in mice by promoting cell proliferation and angiogenesis (Wang et al., 2017)

How GHK-CU works

GHK-Cu is studied to act through three distinct molecular routes: transcriptional reprogramming, extracellular matrix remodeling, and redox regulation.

Gene modulationtranscriptional reprogramming

ECM remodelingMMP / TIMP axis

Redox regulationantioxidant pathway

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Search

Search

Search

GHK-CU

Every vial ships with its own report

What is GHK-CU?

What the research actually found

How GHK-CU works

Gene modulationtranscriptional reprogramming

ECM remodelingMMP / TIMP axis

Redox regulationantioxidant pathway

How every batch is verified

Researchers reach for these

Frequently asked

What is GHK-Cu and where does it come from?

What has preclinical research shown about GHK-Cu's activity?

Is GHK-Cu FDA approved?

How is GHK-Cu used in current research settings?

What is the molecular structure of GHK-Cu?

How should GHK-Cu be stored?

≥98% pure — or your money back.

Search

Search

GHK-CU

Every vial ships with its own report

What is GHK-CU?

What the research actually found

How GHK-CU works

Gene modulationtranscriptional reprogramming

ECM remodelingMMP / TIMP axis

Redox regulationantioxidant pathway

How every batch is verified

Researchers reach for these

Frequently asked

What is GHK-Cu and where does it come from?

What has preclinical research shown about GHK-Cu's activity?

Is GHK-Cu FDA approved?

How is GHK-Cu used in current research settings?

What is the molecular structure of GHK-Cu?

How should GHK-Cu be stored?

≥98% pure — or your money back.